Ocimum tenuiflorum, leaf. Ayurveda’s “incomparable one”, a peppery, clove-scented cousin of kitchen basil. Sold today as an adaptogen for everyday stress.
What the research supports
- Stress: placebo-controlled trials (2012, 2022) found lower stress scores after six to eight weeks, and the 2022 trial also found lower hair cortisol.
- Sleep: the 2022 trial reported better sleep quality than placebo.
- Anxiety: one small, older study without a placebo group suggested a benefit.
- Blood sugar: small trials found a modest drop in fasting blood sugar.
The dose that was actually studied
125 mg of a standardized extract twice a day (2022 trial), or 1,000 to 1,200 mg a day of general extract in older trials. For liquid extracts, follow the label.
Who should not take it
- Pregnant women and couples trying to conceive.
- People on diabetes medication or blood thinners, and anyone with surgery in the next two weeks.
- People with an underactive thyroid, unless their doctor agrees.
Our take
One of the better-studied stress herbs. Expect it to take the edge off, not replace proper care. Read our full holy basil stress guide for every study and the details.
Our pick
Hawaii Pharm Holy Basil (Tulsi) Alcohol-Free Liquid Extract: Holy basil leaf in an alcohol-free glycerite, easy to add to water or evening tea.
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For general education only, not medical advice. Talk to your doctor or pharmacist before starting a supplement, especially if you take medication or are pregnant or breastfeeding.
